ENGLISH

Publications

業績

英文原著

(* corresponding author)

2017

Nashimoto Y, Hayashi T, Kunita I, Nakamasu A, Torisawa YS, Nakayama M, Takigawa-Imamura H, Kotera H, Nishiyama K, Miura T, Yokokawa R.Integrating perfusable vascular networks with a three-dimensional tissue in a microfluidic device. Integr Biol (Camb) 9(6):506-518, 2017. doi: 10.1039/c7ib00024c.

2015

Sugihara K#, Nishiyama K#*, Fukuhara S, Uemura A, Arima S, Kobayashi R, Köhn-Luque A, Mochizuki N, Suda T, Ogawa H, Kurihara H. #These authors contributed equally to this work. Autonomy and non-autonomy of angiogenic cell movements revealed by experiment-driven mathematical modeling. Cell Rep, 13(9):1814-27, 2015. http://dx.doi.org/10.1016/j.celrep.2015.10.051.

Sueta D, Yamamoto E, Tanaka T, Hirata Y, Sakamoto K, Tsujita K, Kojima S, Nishiyama K, Kaikita K, Hokimoto S, Jinnouchi H, Ogawa H. The accuracy of central blood pressure waveform by novel mathematical transformation of non-invasive measurement. Int J Cardiol 189:244-61, 2015. DOI: 10.1016/j.ijcard.2015.03.182.

2014

Arita Y, Nakaoka Y, Matsunaga T, Kidoya H, Yamamizu K, Arima Y, Kataoka-Hashimoto T, Ikeoka K, Yasui T, Masaki T, Yamamoto K, Higuchi K, Park JS, Shirai M, Nishiyama K, Yamagishi H, Otsu K, Kuriara H., Minami T, Yamauchi-Takihara K, Koh GY, Mochizuki N, Takakura N, Sakata Y, Yamashita JK, and Komuro I. Myocardium-derived angiopoietin-1 is essential for coronary vein formation in the developing heart. Nat Commun 5:4452, 2014. DOI: 10.1016/j.ijcard.2015.03.182

2013

Kim KS, Arima Y, Kitazawa T, Nishiyama K, Asai R, Uchijima Y, Sato T, Levi G, Kitanaka S, Igarashi T, Kurihara Y, & Kurihara H. Endothelin regulates neural crest deployment and fate to form great vessels through Dlx5/Dlx6-independent mechanisms. Mech Dev 130(11-12):553-66, 2013. DOI: 10.1016/j.mod.2013.07.005

Fukushima T, Kamata H, Nishimura F, Kikuchi T, Fujishiro M, Nishiyama K, Aburatani H, Kushiyama S, Iizuka M, Taki N, Encinas J, Sentani K, Ogonuki N, Ogura A, Kawazu S, Yasui W, Higashi Y, Kurihara H, Katagiri H, Asano T. Resistin-like molecule β is abundantly expressed in foam cells and is involved in atherosclerosis development. Arterioscler Thromb Vasc Biol 33(8):1986-92, 2013. DOI: 10.1161/ATVBAHA.113.301546

2012

Arima Y, Miyagawa-Tomita S, Maeda K, Asai R, Seya D, Minoux M, Rijli FM, Nishiyama K, Kim KS, Uchijima Y, Ogawa H, Kurihara Y, Kurihara H. Preotic neural crest cells contribute to coronary artery smooth muscle involving endothelin signalling. Nat Commun 3:1267, 2012. DOI: 10.1038/ncomms2258

2011

Arima S#, Nishiyama K#*, Ko T, Arima Y, Hakozaki Y, Sugihara K, Koseki H, Uchijima Y, Kurihara Y, Kurihara H. #These authors contributed equally to this work. Angiogenic morphogenesis driven by dynamic and heterogeneous collective endothelial cell movement. Development 138(21):4763-76, 2011. DOI: 10.1242/dev.06802

Kitazawa T, Sato T, Nishiyama K, Asai R., Arima Y, Uchijima Y, Kurihara Y, Kurihara H. Identification and developmental analysis of endothelin receptor type-A expressing cells in the mouse kidney. Gene Exp Pattern 11(7):371-7, 2011. DOI: 10.1016/j.gep.2011.04.001

Tonami K, Kurihara Y, Arima S, Nishiyama K, Uchijima Y, Asano T, Sorimachi H, Kurihara H. Calpain-6, a microtubule-stabilizing protein, regulates Rac1 activity and cell motility through interaction with GEF-H1. J Cell Sci 124:1214-23, 2011. DOI: 10.1242/jcs.072561

2010

Tanaka A, Itoh F, Nishiyama K, Takezawa T, Kurihara H, Itoh S, Kato M. Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis. Blood 115(20):4138-44, 2010. DOI: 10.1182/blood-2009-05-223057

Asai R, Kurihara Y, Fujisawa K, Sato T, Kawamura Y, Kokubo H, Tonami K, Nishiyama K, Uchijima Y, Miyagawa-Tomita S, Kurihara H. Endothelin receptor type A expression defines a distinct cardiac subdomain within the heart field and is later implicated in chamber myocardium formation. Development 518(23):4702-22, 2010. DOI: 10.1242/dev.054015

Kawamura Y, Uchijima Y, Horike N, Tonami K, Nishiyama K, Amano T, Asano T, Kurihara Y, Kurihara H. Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest. J. Clin Invest 120(8): 2817-28, 2010. DOI: 10.1172/JCI42020

Fujimoto C, Ozeki H, Uchijima Y, Suzukawa K, Mitani A, Fukuhara S, Nishiyama K, Kurihara Y, Kondo K, Aburatani H, Kaga K, Yamasoba T, Kurihara H. Establishment of mice expressing EGFP in the placode-derived inner ear sensory cell lineage and FACS-array analysis focused on the regional specificity of the otocyst. J. Comp Neurol 518(23): 4702-22, 2010. DOI: 10.1002/cne.22468

2008

Horike N, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Kamata H, Nishiyama K, Uchijima Y, Kurihara Y, Kurihara H, Asano T.AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver. J Biol Chem 283(49): 33902-10, 2008. DOI: 10.1074/jbc.M802537200

Makita R, Uchijima Y, Nishiyama K, Amano T, Chen Q, Takeuchi T, Mitani A, Nagase T, Yatomi Y, Aburatani H, Nakagawa O, Small EV, Cobo-Stark P, Igarashi P, Murakami M, Tominaga J, Sato T, Asano T, Kurihara Y, Kurihara H. Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ. Am J Physiol Renal Physiol 294(3):F542-53, 2008. DOI: 10.1152/ajprenal.00201.2007

2007

Nishiyama K.* , Takaji K., Uchijima Y., Kurihara Y., Asano T., Yoshimura M., Ogawa H., Kurihara H. Protein kinase A-regulated nucleocytoplasmic shuttling of Id1 during angiogenesis. J Biol Chem 282(23):17200-9, 2007.
DOI: 10.1074/jbc.M611609200

2005

Nishiyama K*, Takaji K, Kataoka K, Kurihara Y, Yoshimura M, Kato K, Ogawa H, Kurihara H. Id1 Gene Transfer Confers Angiogenic Property on Fully Differentiated Endothelial Cells and Contributes to Therapeutic Angiogenesis.
Circulation 112:2840-2850, 2005.
DOI: 10.1161/CIRCULATIONAHA.104.516898

Kushiyama A, Shojima N, Ogihara T, Inukai K, Sakoda H, Fujishiro M, Fukushima Y, Anai M, Ono H, Horike N, Viana AY, Uchijima Y, Nishiyama K, Shimosawa T, Fujita T, Katagiri H, Oka Y., Kurihara H, Asano T. Resistin like molecule beta activates MAPKs, suppresses insulin signaling in hepatocytes and induces diabetes, hyperlipidemia and fatty liver in transgenic mice on a high-fat diet. J Biol Chem 280(51):42016-25, 2005.
DOI: 10.1074/jbc.M503065200

2001

Nishiyama K, Yasue H, Moriyama Y, Tsunoda R, Ogawa H, Yoshimura M, Kugiyama K. Acute effects of melatonin administration on cardiovascular autonomic regulation in healthy men. Am Heart J 141(5):E9, 2001.

2000

Ogawa H, Suefuji H, Soejima H, Nishiyama K, Misumi K, Takazoe K, Miyamoto S, Kajiwara I, Sumida H, Sakamoto T, Yoshimura M, Kugiyama K, Yasue H, Matsuo K. Increased blood vascular endothelial growth factor levels in patients with acute myocardial infarction. Cardiology 93(1-2):93-9, 2000. DOI: 10.1159/000007008

Moriyama Y, Yasue H, Yoshimura M, Mizuno Y, Nishiyama K, Tsunoda R, Kawano H, Kugiyama K, Ogawa H, Saito Y, Nakao K. The plasma levels of dehydroepiandrosterone sulfate are decreased in patients with chronic heart failure in proportion to the severity. J Clin Endocrinol Metab 85(5):1834-40, 2000. DOI: 10.1210/jc.85.5.1834

Ogawa H, Sakamoto T, Nishiyama K, Soejima H, Kaikita K, Takazoe K, Miyamoto S, Kugiyama K, Yoshimura M, Yasue H. Elevated levels of soluble intercellular adhesion molecule-1 in the coronary circulation of patients with coronary organic stenosis and spasm. Jpn Circ J 64(3):170-6, 2000. DOI: 10.1253/jcj.64.170

1999

Soejima H, Ogawa H, Yasue H, Kaikita K, Takazoe K, Nishiyama K, Misumi K, Miyamoto S, Yoshimura M, Kugiyama K, Nakamura S, Tsuji I. Angiotensin-converting enzyme inhibition reduces monocyte chemoattractant protein-1 and tissue factor levels in patients with myocardial infarction. J Am Coll Cardiol 34(4):983-8, 1999. DOI: 10.1016/S0735-1097(99)00318-6

Soejima H, Ogawa H, Yasue H, Kaikita K, Nishiyama K, Misumi K, Takazoe K, Miyao Y, Yoshimura M, Kugiyama K, Nakamura S, Tsuji I, Kumeda K. Heightened tissue factor associated with tissue factor pathway inhibitor and prognosis in patients with unstable angina. Circulation 99(22):2908-13, 1999.

Ogawa H, Yasue H, Miyao Y, Sakamoto T, Soejima H, Nishiyama K, Kaikita K, Suefuji H, Misumi K, Takazoe K, Kugiyama K, Yoshimura M. Plasma soluble intercellular adhesion molecule-1 levels in coronary circulation in patients with unstable angina. Am J Cardiol 83(1):38-42, 1999.
DOI: 10.1016/S0002-9149(98)00779-6

Soejima H, Ogawa H, Yasue H, Nishiyama K, Kaikita K, Misumi K, Takazoe K, Kugiyama K, Tsuji I, Kumeda K, Nakamura S. Plasma tissue factor pathway inhibitor and tissue factor antigen levels after administration of heparin in patients with angina pectoris. Thromb Res 93(1):17-25, 1999. DOI: 10.1016/S0049-3848(98)00147-9

1998

Moriyama Y, Ogawa H, Oshima S, Arai H, Takazoe K, Shimomura H, Hirai N, Suefuji H, Soejima H, Nishiyama K, Misumi K, Yasue H. Relationship between serum angiotensin-converting enzyme activity and plasma plasminogen activator inhibitor activity in patients with recent myocardial infarction. Coron Artery Dis 9(10):691-6, 1998.
Nishiyama K, Ogawa H, Yasue H, Soejima H, Misumi K, Takazoe K, Yoshimura M, Kugiyama K, Tsuji I, Kumeda K. Simultaneous elevation of the levels of circulating monocyte chemoattractant protein-1 and tissue factor in acute coronary syndromes. Jpn Circ J 62(9):710-2, 1998. DOI: 10.1253/jcj.62.710

Misumi K, Ogawa H, Yasue H, Soejima H, Suefuji H, Nishiyama K, Takazoe K, Kugiyama K, Tsuji I, Kumeda K. Circadian variation in plasma levels of free-form tissue factor pathway inhibitor antigen in patients with coronary spastic angina. Jpn Circ J 62(6):419-24, 1998. DOI: 10.1253/jcj.62.419

Nishiyama K, Ogawa H, Yasue H, Soejima H, Misumi K, Kugiyama K, Tsuji I, Kumeda K. Heparin-releasable endothelial cell-associated tissue factor pathway inhibitor (TFPI) is increased in the coronary circulation after coronary spasm in patients with coronary spastic angina. Thromb Res 89(3):137-46, 1998. DOI: 10.1016/S0049-3848(97)00309-5

Shimomura H., Ogawa H., Arai H., Moriyama Y., Takazoe K., Hirai N., Kaikita K., Hirashima O., Misumi K., Soejima H., Nishiyama K., Yasue H. Serial changes in plasma levels of soluble P-selectin in patients with acute myocardial infarction. Am J Cardiol 81(4):397-400, 1998. DOI: 10.1016/S0002-9149(97)00945-4

Misumi K, Ogawa H, Yasue H, Soejima H, Suefuji H, Nishiyama K, Takazoe K, Kugiyama K, Tsuji I, Kumeda K, Nakamura S. Comparison of plasma tissue factor levels in unstable and stable angina pectoris. Am J Cardiol 81(1):22-6, 1998. DOI: 10.1016/S0002-9149(97)00801-1

1997

Soejima H, Ogawa H, Yasue H, Suefuji H, Kaikita K, Nishiyama K. Effects of imidapril therapy on endogenous fibrinolysis in patients with recent myocardial infarction. Clin Cardiol 20(5):441-5, 1997.

1996

Suefuji H, Ogawa H, Yasue H, Imoto N, Sakamoto T, Miyao Y, Kaikita K, Soejima H, Nishiyama K. Effect of niceritrol on fibrinolysis and lipoprotein (a) levels in patients with coronary artery disease. Coron Artery Dis 7(2), 167-72 (1996). DOI: 10.1097/00019501-199602000-00012

1995

Saito T, Yashita S, Noda K, Mizuno Y, Kawabata S, Higa T, Nakahashi E, Iwasa A, Nishiyama K, Ohshima S. Clinical experience with the ACS RX Lifestream coronary dilatation catheter: a new low profile perfusion balloon catheter. J Invasive Cardiol 7 Suppl B:39B-45B, discussion 50B-56B, 1995.

日本語総説

西山功一 血管作りに秘められた細胞集団の挙動 細胞工学 33(6): 639-643, 2014

栗原裕基、有馬聡、西山功一 血管新生の細胞動態解析 生体の科学 65(5):428-429, 2014

西山功一 in vitroライブイメージングと定量解析による血管新生機構の解明 日本血栓止血学会誌  24(6): 553-559, 2013

西山功一 「Id」血管生物医学事典 375-77, 2011

西山功一 「NO, NOS」血管生物医学事典 95-7, 2011

藤沢興、西山功一「エンドセリン」血管生物医学事典112-3, 2011

西山功一、有馬聡、栗原裕基.「In vitro ライブイメージングによる血管新生機構の解明.」 血管医学 11(3):77-84, 2010

西山功一、 栗原 裕基 各分野におけるノーベル賞の貢献 循環器疾患. 総合臨床 57(1):54-60, 2008

西山功一 血管の生理と病態モデル 虚血. 血管医学 8(2):79-86, 2007

西山功一 血管内皮前駆細胞 循環器科 60(5):449-456, 2006

西山功一、栗原裕基 血管新生と内皮前駆細胞:血管内皮細胞をめぐる疾患(島田和幸編) 29-42, 2006